Metabolic Health & Body Composition
AOD-9604
Studied in lipolysis research
A growth-hormone fragment originally studied for fat metabolism — included for context, though Phase 2b trials did not show meaningful weight reduction.
Overview
AOD-9604 is a 16-amino-acid synthetic fragment of human growth hormone studied in the context of lipolysis. Phase 2b human trials sponsored by the original developer did not meet primary efficacy endpoints for clinically meaningful fat loss compared to placebo, and pharmaceutical development for the obesity indication was discontinued in 2007. We discuss this candidly.
Evidence: primarily pre-clinical / limited human data
In consultation, clients often ask
The fact that the Phase 2b trial did not demonstrate meaningful weight reduction.
Why this is not a substitute for the GLP-1 conversation.
Regulatory & sourcing
Not FDA-approved. Currently Category 2 / not permitted for compounding on the 503A bulks list. Discussed candidly during consultation.
References
Stier H, Vos E, Kenley D. Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans. Journal of Endocrinology and Metabolism.
Heffernan M, et al. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism. Endocrinology.
Please read
Peptide therapy at Jaed Aesthetics is offered as a private wellness consultation service. None of the peptides discussed on this menu are FDA-approved for the wellness areas described, and some are investigational or available only through compounding pharmacies operating under FDA Sections 503A or 503B. Several peptides on this menu have primarily pre-clinical or animal evidence and limited published human data; we note this honestly under each entry. Any decision to proceed, the specific peptide selected, route of administration, dosing, monitoring, and pricing are determined one-on-one with our nurse practitioner during consultation. Nothing on this page constitutes medical advice, a diagnosis, or a treatment recommendation.
By consultation
Schedule a peptide consultation, in the basin.
Pricing, availability, and treatment plans are determined one-on-one. Bring your goals — we'll work the plan from there.