Recovery & Repair
IGF-1 LR3
Researched in anabolism and sarcopenia
Used to support muscle growth and recovery in research contexts — one of the more carefully gated conversations on this menu given the class-level safety considerations.
Overview
IGF-1 LR3 is a modified analog of insulin-like growth factor 1 with reduced binding-protein affinity and extended action. It is discussed in the context of anabolism and sarcopenia research. There are no published human clinical trials of IGF-1 LR3 itself; the closest human dataset comes from the FDA-approved native rhIGF-1 (mecasermin / Increlex) used only in pediatric severe primary IGF-1 deficiency.
Evidence: primarily pre-clinical / limited human data
In consultation, clients often ask
Why this peptide is more closely supervised than others on the menu.
The hypoglycemia and tumor-signaling questions raised in the IGF-1 class literature.
Regulatory & sourcing
Not on the 503A bulks list. WADA-prohibited. Class-level safety concerns documented in the Increlex label include hypoglycemia (reported in 42% of treated subjects), intracranial hypertension, lymphoid hyperplasia, and tumor risk. This is one of the more carefully gated conversations on the menu.
References
Bailes J, Soloviev M. Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in Medical Diagnostic and in Sports. Int J Mol Sci. 2021 (PMC7913862).
FDA Increlex (mecasermin) prescribing information — class-level safety reference.
Please read
Peptide therapy at Jaed Aesthetics is offered as a private wellness consultation service. None of the peptides discussed on this menu are FDA-approved for the wellness areas described, and some are investigational or available only through compounding pharmacies operating under FDA Sections 503A or 503B. Several peptides on this menu have primarily pre-clinical or animal evidence and limited published human data; we note this honestly under each entry. Any decision to proceed, the specific peptide selected, route of administration, dosing, monitoring, and pricing are determined one-on-one with our nurse practitioner during consultation. Nothing on this page constitutes medical advice, a diagnosis, or a treatment recommendation.
By consultation
Schedule a peptide consultation, in the basin.
Pricing, availability, and treatment plans are determined one-on-one. Bring your goals — we'll work the plan from there.