Cognitive Health & Mood
Pinealon
Researched in CNS signaling
A short Khavinson peptide used to support cognitive function, neuroprotection, and central nervous system signaling.
Overview
Pinealon is a Khavinson tripeptide (Glu-Asp-Arg, EDR) studied in the context of central-nervous-system signaling and neuroprotection. The strongest indexed paper is an in vitro mouse hippocampal-neuron study under amyloid stress. No Phase 1/2/3 human trials exist on ClinicalTrials.gov; the largest human-use observation is a 72-patient open-label series in Russian post-TBI cerebrasthenia by the developer's own group.
Evidence: primarily pre-clinical / limited human data
In consultation, clients often ask
The candid limits of the evidence base.
Why this is treated as a research-context conversation, not standard care.
Regulatory & sourcing
Not FDA-approved. Not on the 503A bulks list. Evidence is dominated by a single research group with no independent Western replication.
References
Kraskovskaya NA, et al. Tripeptides Restore the Number of Neuronal Spines under Conditions of In Vitro Modeled Alzheimer's Disease. Bull Exp Biol Med. 2017; PMID 28853087.
Khavinson VK, et al. Short Peptides and Telomere Length Regulator Hormone Irisin: Similarities of Anti-Aging Effects.
Please read
Peptide therapy at Jaed Aesthetics is offered as a private wellness consultation service. None of the peptides discussed on this menu are FDA-approved for the wellness areas described, and some are investigational or available only through compounding pharmacies operating under FDA Sections 503A or 503B. Several peptides on this menu have primarily pre-clinical or animal evidence and limited published human data; we note this honestly under each entry. Any decision to proceed, the specific peptide selected, route of administration, dosing, monitoring, and pricing are determined one-on-one with our nurse practitioner during consultation. Nothing on this page constitutes medical advice, a diagnosis, or a treatment recommendation.
By consultation
Schedule a peptide consultation, in the basin.
Pricing, availability, and treatment plans are determined one-on-one. Bring your goals — we'll work the plan from there.